Beyond sports-doping headlines: the science of laboratory tests for performance-enhancing drugs
Pediatr Clin North Am. 2007 Aug;54(4):713-733
Hatton CK.
UCLA Olympic Laboratory, University of California at Los Angeles, 2122 Granville Avenue, Los Angeles, CA 90025, USA.
PubMed ID & Record: 17723873
This primer on urine analysis in sports-doping control is an overview with an emphasis on the main analytical chemistry technologies in use: gas chromatography-mass spectrometry (GC-MS), liquid chromatography-tandem mass spectrometry (LC-MS-MS), isotope ratio mass spectrometry detection of exogenous testosterone use, and isoelectric focusing detection of recombinant erythropoietin (EPO) use. Included are graphic examples of GC-MS selected ion monitoring and full scan, LC-MS-MS, and EPO test electropherogram data; a list of common acronyms; and answers to questions frequently asked about tampering and test accuracy.
Hatton CK.
UCLA Olympic Laboratory, University of California at Los Angeles, 2122 Granville Avenue, Los Angeles, CA 90025, USA.
PubMed ID & Record: 17723873
This primer on urine analysis in sports-doping control is an overview with an emphasis on the main analytical chemistry technologies in use: gas chromatography-mass spectrometry (GC-MS), liquid chromatography-tandem mass spectrometry (LC-MS-MS), isotope ratio mass spectrometry detection of exogenous testosterone use, and isoelectric focusing detection of recombinant erythropoietin (EPO) use. Included are graphic examples of GC-MS selected ion monitoring and full scan, LC-MS-MS, and EPO test electropherogram data; a list of common acronyms; and answers to questions frequently asked about tampering and test accuracy.
posted by Dr.Koudinov @ 1:21 AM
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